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TRAF6 polyclonal antibody

ADI-AAP-426-E 100 µl 362.00 USD
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Product Details

Alternative Name:TNF receptor-associated factor 6
Immunogen:Recombinant mouse TRAF6 (N-terminal fragment).
UniProt ID:P70196
Species reactivity:Mouse
Applications:IP, WB
Recommended Dilutions/Conditions:Immunoprecipitation (2-4µL/100-500 µl cell extract from 5x106 cells)
Western Blot (1:1000, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~58kDa by Western blot.
Purity Detail:Immunoaffinity purified.
Formulation:Liquid. In PBS containing 50% glycerol.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:TRAF proteins are multifunctional signal adaptors that are involved in the activation of the kinase cascades which activate c-Jun N-terminal kinase, p38 mitogen activated protein kinase, and the transcription factor NF-κB. Members of the TRAF family form homodimers as well as heterodimers, resulting in extensive diversity and specificity to their function in signal transduction pathways.
Regulatory Status:RUO - Research Use Only
TRAF6 polyclonal antibody Western blot
Western blot analysis of L5178Y (1), WR19L (2) and NIH/3T3 (3) cells, probed with TRAF6 pAb.
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TRAF6 polyclonal antibody Western blot

Product Literature References

A high-throughput pipeline for validation of antibodies: K. Sikorski, et al.; Nat. Methods 15, 909 (2018), Abstract;
The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis: T. Izawa, et al.; J. Immunol. 197, 4639 (2016), Abstract; Full Text

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