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Cytochrome c polyclonal antibody

ADI-AAP-170-E 100 µg 410.00 USD
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Product Details

Alternative Name:Cyt c
Immunogen:Full length recombinant cytochrome C.
UniProt ID:P99999 (human), P62898 (rat), P00008 (rabbit), P00011 (dog)
Gene/Protein Identifier:NP_031834 (RefSeq)
Species reactivity:Human, Rat
Dog, Rabbit
Applications:IHC, IP, WB
Recommended Dilutions/Conditions:Western Blot (1:5,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~14kDa by Western blot.
May be used in immunofluorescence applications with human and rat cells.
Purity Detail:Affinity purified.
Formulation:Liquid. In PBS containing 0.08% sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:Cytochrome c, which is a critical component of the electron transport chain, is a component of the functional apoptosome. Upon release from the mitochondria, cytochrome c binds to the adaptor proteins Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex. This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death.
Regulatory Status:RUO - Research Use Only
Cytochrome c polyclonal antibody Western blot
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Cytochrome c polyclonal antibody Western blot

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