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Bcl-xL monoclonal antibody (2H12)

ADI-AAM-080-E 100 µg 389.00 USD
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Product Details

Alternative Name:BCL2L1
Immunogen:Synthetic peptide corresponding to the sequence near the N-terminus of human Bcl-xL.
UniProt ID:Q07817
Gene/Protein Identifier:B47537 (PIR)
Species reactivity:Human, Mouse, Rat
Recommended Dilutions/Conditions:Western Blot (1-5µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~28kDa by Western blot.
Purity Detail:Ascites.
Formulation:Liquid. In PBS containing 0.08% sodium azide.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:The Bcl-2 family of proteins regulate the intrinsic apoptotic pathway and are characterized by the sharing of at least one of four conserved Bcl-2 Homology (BH) domains. Bcl-2 family members function as either pro- or anti-apoptotic factors, and are generally categorized into three groups based on structural homology and function. Bcl-2-like proteins (Bcl-2, Bcl-xL, Bcl-w, A1, and Mcl-1) are pro-survival. Pro-apoptotic members can be sub-divided into two groups: the multi-BH domain group, including Bax, Bak, and Bok; and the more numerous and diverse BH3-only group, which includes Bim, Bad, and Bid.
Regulatory Status:RUO - Research Use Only
Bcl-xL monoclonal antibody (2H12) Western blot
Western blot analysis of thymocytes from human, mouse and rat, probed with Bcl-xL mAb (2H12).
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Bcl-xL monoclonal antibody (2H12) Western blot

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