HIGHDEF® blue IHC chromogen (HRP) is intended to be used in conjunction with horseradish peroxidase (HRP)-based immunostaining or in situ hybridization (ISH) systems.
Immunohistochemistry analysis: Formalin fixed paraffin embedded human tonsil stained with a high molecular weight cytokeratin antibody labeled and HIGHDEF® blue IHC chromogen (HRP) (Prod. no. ADI-950-151) produces a brilliant blue color.
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Product Details
Applications:
IHC ISH (in situ hybridization)
Contents:
HIGHDEF® blue IHC chromogen (HRP) substrate buffer and chromogen, Empty mixing bottle
The HIGHDEF® blue IHC chromogen (HRP) is a substrate-chromogen system designed to be used for either immunohistochemistry (IHC) or ISH when utilizing horseradish peroxidase. HIGHDEF® blue IHC chromogen (HRP) produces a sharply contrasting billiant blue color that can easily be distinguished from other stains.
Regulatory Status:
RUO - Research Use Only
Product Literature References
Plasma cells, plasmablasts, and AID+/CD30+ B lymphoblasts inside and outside germinal centres: details of the basal light zone and the outer zone in human palatine tonsils: B.S. Steiniger, et al.; Histochem. Cell Biol. 154, 55 (2020), Abstract; Full Text
CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy: W. Wang, et al.; Nature 569, 270 (2019), Abstract; Full Text
Characterization of non-hormone expressing endocrine cells in fetal and infant human pancreas: A.S.M. Moin, et al.; Front. Endocrinol. 9, 791 (2019), Abstract; Full Text
Age-and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease: X. Hou, et al.; Autophagy 14, 1404 (2018), Abstract; Full Text
Platelet lysate-derived neuropeptide y influences migration and angiogenesis of human adipose tissue-derived stromal cells: R. Businaro, et al.; Sci. Rep. 8, 14365 (2018), Abstract; Full Text
Altered dermal fibroblasts in systemic sclerosis display podoplanin and CD90: B. Nazari, et al.; Am. J. Pathol. 186, 2650 (2016), Abstract; Full Text
Clonorchis sinensis omega-class glutathione transferases play major roles in the protection of the reproductive system during maturation and the response to oxidative stress: J.G. Kim, et al.; Parasit. Vectors 9, 337 (2016), Application(s): IHC using formaldehyde-fixed embedded adult worm sections, Abstract; Full Text
Expression of programmed cell death 1 ligands (PD-L1 and PD-L2) in histiocytic and dendritic cell disorders: J. Xu, et al.; Am. J. Surg. Pathol. 40, 443 (2016), Abstract;
Smooth muscle Hgs deficiency leads to impaired esophageal motility: J. Chen, et al.; Int. J. Biol. Sci. 11, 794 (2015), Abstract; Full Text
Young investigator challenge: Application of cytologic techniques to circulating tumor cell specimens: Detecting activation of the oncogenic transcription factor STAT3: A.C. Lowe, et al.; Cancer Cytopathol. 123, 696 (2015), Abstract;
Expression of programmed cell death 1 ligand 2 (PD-L2) is a distinguishing feature of primary mediastinal (thymic) large B-cell lymphoma and associated with PDCD1LG2 copy gain: M. Shi, et al.; Am. J. Surg. Pathol. 38, 1715 (2014), Abstract;
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