| Alternative Name: | VIM |
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| MW: | ~86kDa (including GST-tag) |
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| Source: | Produced in E. coli. |
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| UniProt ID: | P08670 |
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| Formulation: | Liquid. In 50mM Tris-HCl, pH 7.5, containing 10mM L-glutathione (reduced). |
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| Purity Detail: | Purified by multi-step chromatography. |
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| Applications: | ELISA, WB
Inhibition assay
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| Application Notes: | Western blot control. |
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| Shipping: | Shipped on Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | Vimentin is an ~58 kDa intermediate filament protein distributed widely in the cytoplasm and is phosphorylated by several protein kinases in vitro. Components of intermediate filaments provide information on the origin of vertebrate cells. Antibody to vimentin can be used as to identify the vimentin subclass of intermediate filaments. Vimentin is a widely expressed protein that is thought to be involved mainly in structural processes, such as wound healing. Researchers have also determined that activated human macrophages secrete vimentin into the extracellular space, and overproduction of vimentin has been associated with cellular senescence. |
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| Regulatory Status: | RUO - Research Use Only |
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