Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

LTC4 monoclonal antibody (6E7)

ADI-905-902-0050 50 µg 227.00 USD
ADI-905-902-0200 200 µg 467.00 USD
Do you need bulk/larger quantities?

Product Details

Alternative Name:Leukotriene C4
Immunogen:Leukotriene C4
Source:Purified from mouse ascites.
Species reactivity:Human, Mouse, Rat
Recommended Dilutions/Conditions:Radioimmunoassay (1:1,000)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Purity Detail:Protein G affinity purified.
Formulation:Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Handling:Avoid freeze/thaw cycles.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:Leukotrienes are metabolic products of arachidonic acid formed by the action of 5-lipoxygenase (5-LO), with the principal products being leukotrienes C4 (LTC4) and B4 (LTB4). Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.
Regulatory Status:RUO - Research Use Only

General Literature References

International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors: C. Brink, et al.; Pharmacol. Rev. 55, 195 (2003), Abstract;
Leukotriene B4: metabolism and signal transduction: T. Yokomizo, et al.; Arch. Biochem. Biophys. 385, 231 (2001), Abstract;

Product Toolbox


Certificate of Analysis


By target:
Leukotriene synthase
By biological activity:
Leukotriene synthase Monoclonal antibody
By catalog section:


Technical Service
Customer Service

Recommend this page

Keep in touch

©2021 Enzo Life Sciences, Inc.,