Alternative Name: | FGF1 |
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Clone: | 4D2 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Recombinant human aFGF (fibroblast growth factor 1) (aa 16-155). |
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UniProt ID: | P05230 |
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Species reactivity: | Human
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Applications: | WB
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Recommended Dilutions/Conditions: | Western Blot (1:50,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~17kDa (full length) by Western blot. |
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Purity Detail: | Protein G affinity purified. |
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Formulation: | Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. |
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Regulatory Status: | RUO - Research Use Only |
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