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TLR3 polyclonal antibody

ADI-905-726-100 100 µg 478.00 USD
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Product Details

Alternative Name:Toll-like receptor 3
Immunogen:Synthetic peptide corresponding to the sequence near the C-terminus of human TLR3.
UniProt ID:O15455
Species reactivity:Human, Mouse
Applications:ICC, WB
Recommended Dilutions/Conditions:Immunocytochemistry (1µg/ml)
Western Blot (1-2µg/ml)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
Application Notes:Detects a band of ~106kDa by Western blot.
Purity Detail:Affinity chromatography purified via peptide column.
Formulation:Liquid. In PBS containing 0.02% sodium azide.
Shipping:Blue Ice
Long Term Storage:-20°C
Scientific Background:The TLRs (Toll-like receptors) are a group of evolutionarily conserved pattern recognition molecules that play a key role in host defense during microbial infection by regulating both innate and adaptive immune responses. TLRs are type I transmembrane proteins with ectodomains containing interspersed leucine-rich repeat (LRR) motifs that are involved in the recognition of various microbial ligands.
Regulatory Status:RUO - Research Use Only
TLR3 polyclonal antibody Immunocytochemistry
Immunocytochemistry analysis of TLR3 in EL4 cells with TLR3 antibody at 1µg/ml.
TLR3 polyclonal antibody Western blot
Western blot analysis of TLR3 in Daudi cell lysate with TLR3 antibody at (A) 1 and (B) 2µg/ml.
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TLR3 polyclonal antibody Immunocytochemistry TLR3 polyclonal antibody Western blot

Product Literature References

Toll-like receptor 3 signaling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells: T. Imaizumi, et al.; Clin. Exp. Nephrol. 19, 761 (2015), Abstract;
Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells: T. Imaizumi, et al.; Am. J. Nephrol. 37, 118 (2013), Abstract;

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