Alternative Name: | Hamartin, Tuberous sclerosis 1 protein |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to the sequence near the middle of human TSC1. |
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UniProt ID: | Q92574 |
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Species reactivity: | Human, Mouse, Rat
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Applications: | ICC, WB
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Recommended Dilutions/Conditions: | Immunocytochemistry (2µg/ml) Western Blot (1µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Peptide affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | +4°C |
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Scientific Background: | Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 (Hamartin) or TSC2 (Tuberin) tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases mTOR signaling via stimulation of Rheb GTPase activity. |
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Regulatory Status: | RUO - Research Use Only |
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