| ADI-905-699-100 | 100 µg | 268.00 USD |  |
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| Alternative Name: | SKB, PRDM1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human PRMT1. |
| UniProt ID: | Q99873 |
| Species reactivity: | Human |
| Applications: | ELISA, IHC, WB |
| Recommended Dilutions/Conditions: | ELISA (1:1,000) Immunohistochemistry (1:50-1:100) Western Blot (1:100-1:500) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Protein G affinity purified. |
| Formulation: | Liquid. In PBS containing 0.09% sodium azide. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Protein arginine N-methyltransferases (PRMTs) catalyze the transfer of a methyl group from S-adenosylmethionine (AdoMet) to a guanidine nitrogen of arginine. PRMT1 methylates arginine residues in glycine-rich areas of histone H4 as well as many non-histone substrates that regulate transcriptional activation, mRNA processing, and signal transduction. In contrast, PRMT5 methylates arginines in proline-, glycine-, methionine-rich motifs and is known to interact with Jak kinases. PRMT2 inhibits NF-κB-dependent transcription and promotes apoptosis. |
| Regulatory Status: | RUO - Research Use Only |
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