| ADI-905-693-100 | 100 µg | 299.00 USD |  |
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| Alternative Name: | Interleukin-1 receptor-associated kinase 4 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to a portion of human IRAK4. |
| UniProt ID: | Q9NWZ3 |
| Species reactivity: | Human |
| Applications: | ELISA, IHC, WB |
| Purity Detail: | Protein G affinity purified. |
| Formulation: | Liquid. In PBS containing 0.09% sodium azide. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression. |
| Regulatory Status: | RUO - Research Use Only |
