Alternative Name: | Signal transducer and activator of transcription 1 |
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Clone: | 12C5 |
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Host: | Mouse |
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Isotype: | IgG1 |
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Immunogen: | Synthetic peptide corresponding to a portion of Stat1 phosphorylated at Ser727. |
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UniProt ID: | P42224 |
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Species reactivity: | Human
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Applications: | ELISA, WB
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Recommended Dilutions/Conditions: | ELISA (0.05µg/ml) Western Blot (0.5µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Application Notes: | Detects a band of ~92kDa by Western blot. |
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Purity Detail: | Thiophilic adsorption and size exclusion chromatography purified. |
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Formulation: | Liquid. In PBS containing 50% glycerol, PEG, sucrose, and 0.09% sodium azide. |
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Use/Stability: | Stable at -20°C up to 1 year. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes. |
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Regulatory Status: | RUO - Research Use Only |
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