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[pSer727]Stat1 monoclonal antibody (12C5)

 
ADI-905-670-100 100 µg 389.00 USD
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Product Details

Alternative Name:Signal transducer and activator of transcription 1
 
Clone:12C5
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Synthetic peptide corresponding to a portion of Stat1 phosphorylated at Ser727.
 
UniProt ID:P42224
 
Species reactivity:Human
 
Applications:ELISA, WB
 
Recommended Dilutions/Conditions:ELISA (0.05µg/ml)
Western Blot (0.5µg/ml, ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Application Notes:Detects a band of ~92kDa by Western blot.
 
Purity Detail:Thiophilic adsorption and size exclusion chromatography purified.
 
Formulation:Liquid. In PBS containing 50% glycerol, PEG, sucrose, and 0.09% sodium azide.
 
Use/Stability:Stable at -20°C up to 1 year.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes.
 
Regulatory Status:RUO - Research Use Only
 
[pSer727]Stat1 monoclonal antibody (12C5) Western blot
Western blot analysis of untreated (1), EGF stimulated (2), or pervanadate treated (3) A549 cell lysates with Stat1 (pSer727) mAb, clone 12C5.
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[pSer727]Stat1 monoclonal antibody (12C5) Western blot

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