| ADI-905-641-100 | 100 µg | 526.00 USD |  |
||
| Do you need bulk/larger quantities? | |||||
| Clone: | 8B5 |
| Host: | Mouse |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to a portion of human c-Fos . |
| UniProt ID: | P01100 |
| Species reactivity: | Human, Mouse, Rat Dog |
| Applications: | ELISA, IHC, WB |
| Recommended Dilutions/Conditions: | ELISA (0.1µg/ml) Immunohistochemistry (1:50) Western Blot (0.5µg/ml, ECL) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~50kDa by Western blot. |
| Purity Detail: | Thiophilic adsorption and size exclusion chromatography purified. |
| Formulation: | Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose. |
| Reconstitution: | Reconstitute with 1ml water (15 minutes at room temperature). |
| Use/Stability: | Stable at -80°C up to 1 year, at 4°C up to 3 months. |
| Shipping: | Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | The immediate early gene product c-Fos is expressed following mitogenic stimulation and functions as a sensor for MAPK signal duration. When MAPK activation is sustained, c-Fos is phosphorylated by MAPK at Ser374. Phosphorylation stabilizes the c-Fos protein and primes c-Fos for additional phosphorylation at Thr325. During transient MAPK activation, activity declines before accumulation of the c-Fos protein. |
| Regulatory Status: | RUO - Research Use Only |
