| ADI-905-496-1 | 1 ml | 350.00 USD |  |
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| Alternative Name: | POU2F1, POU domain class 2 transcription factor 1, OTF1, Octamer-binding protein 1 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human Oct-1. |
| UniProt ID: | P14859 |
| Gene/Protein Identifier: | 5451 (Entrez GeneID) |
| Species reactivity: | Human, Mouse, Rat |
| Applications: | IHC |
| Recommended Dilutions/Conditions: | Immunohistochemistry (1:50) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Purity Detail: | Affinity purified. |
| Formulation: | Liquid. In 10mM PBS, pH 7.4, containing BSA and sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | The POU proteins Oct-1 and Oct-2 were identified as protein activities that selectively interact with octamer DNA sequences that regulate immunoglobulin transcription. The DNA-binding domains of Oct-1 and Oct-2 are highly homologous, and both proteins bind octamer DNA with equal affinity in vitro. Oct-1 is widely expressed whereas Oct-2 expression is restricted to the lymphoid and neuronal compartments. |
| Regulatory Status: | RUO - Research Use Only |
