| ADI-905-277-100 | 100 µg | 357.00 USD |  |
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| Alternative Name: | C-C chemokine receptor 5, CD195 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the N-terminus of human CCR5. |
| UniProt ID: | P51681 |
| Species reactivity: | Human |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (20µg/ml) Western Blot (1:1,000-1:2,000) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~40kDa by Western blot. |
| Purity Detail: | DEAE purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Human immunodeficiency virus (HIV) requires co-receptors, in addition to CD4, to infect target cells. Some G protein coupled receptors such as CCR5, CCR4, CCR3, CCR2b, and CCR8 have been identified as HIV co-receptors. Among them, CCR5 (CCCKR-5) is a principal co-receptor for macrophage- and dual-tropic HIV-1 strains fusion and entry of human white blood cells. CCR5 is required for the infection by HIV-1, HIV-2, and SIV. The amino-terminal domain and the extracellular loops of CCR5 serve as HIV binding sites. |
| Regulatory Status: | RUO - Research Use Only |
Goat anti-rabbit IgG, polyclonal antibody (HRP conjugate) |
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| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-300-J | 1 ml | 150.00 USD | |
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