Alternative Name: | Interleukin-1 receptor accessory protein, Interleukin-1 receptor 3, IL-1R3 |
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Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human IL-1RAcP. |
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UniProt ID: | Q9NPH3 |
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Species reactivity: | Human
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Applications: | ICC, WB
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Purity Detail: | Peptide affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | +4°C |
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Scientific Background: | IL-1alpha and IL-1beta signals are transmitted via a dual subunit IL-1 receptor composed of IL-1R1 and the IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP is vital to IL-1 signaling, as it recruits the IL-1 receptor-associated kinase (IRAK) to the receptor complex, initiating NF-κB pathway activation. |
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Regulatory Status: | RUO - Research Use Only |
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