| ADI-905-237-100 | 100 µg | 458.00 USD |  |
||
| Do you need bulk/larger quantities? | |||||
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to the sequence near the N-terminus of human PUMAα. |
| UniProt ID: | Q9BXH1 |
| Species reactivity: | Human |
| Applications: | IHC, WB |
| Recommended Dilutions/Conditions: | Immunohistochemistry (10µg/ml) Western Blot (2-4µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~23kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | -20°C |
| Scientific Background: | PUMA, the p53 upregulated modulator of apoptosis gene, encodes for two BH3 domain-containing proteins referred to PUMAa and PUMAb1. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce Cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
| Regulatory Status: | RUO - Research Use Only |
Goat anti-rabbit IgG, polyclonal antibody (HRP conjugate) |
||||||
| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-300-J | 1 ml | 150.00 USD | |
|||
| Do you need bulk/larger quantities? | ||||||
