Host: | Rabbit |
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Immunogen: | Synthetic peptide corresponding to the sequence near the C-terminus of human FLASH. |
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UniProt ID: | Q9UKL3 |
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Species reactivity: | Human
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Applications: | ICC, WB
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Recommended Dilutions/Conditions: | Western Blot (0.25-0.5µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
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Purity Detail: | Peptide affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
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Shipping: | Blue Ice Not Frozen |
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Long Term Storage: | +4°C |
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Scientific Background: | The FLICE associated huge protein, FLASH, is involved in Fas induced apoptosis. It is recruited to Fas after the receptor crosslinking. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. |
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Regulatory Status: | RUO - Research Use Only |
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