| ADI-905-188-100 | 100 µg | 459.00 USD |  |
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| Alternative Name: | Caspase recruitment domain-containing protein 9 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to aa 521-536 of human CARD-9. |
| UniProt ID: | Q9H257 |
| Species reactivity: | Human |
| Applications: | ICC, WB |
| Recommended Dilutions/Conditions: | Immunocytochemistry (10µg/ml) Western Blot (0.5-1.0µg/ml) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~59kDa by Western blot. |
| Purity Detail: | Peptide affinity purified. |
| Formulation: | Liquid. In PBS containing 0.02% sodium azide. |
| Shipping: | Blue Ice Not Frozen |
| Long Term Storage: | +4°C |
| Scientific Background: | Apoptotic cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD-9 interacts with the CARD activation domain of BCL-10, a pro-apoptotic activator of NF-κB. CARD-9 is thought to act as a scaffold for the assembly of BCL10 signaling complexes associated with the activation of NF-κB. |
| Regulatory Status: | RUO - Research Use Only |
Goat anti-rabbit IgG, polyclonal antibody (HRP conjugate) |
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| ELISA, IHC, WB | Print as PDF | ||||||
| ADI-SAB-300-J | 1 ml | 150.00 USD | |
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