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TMPRSS3 monoclonal antibody (D8)

ADI-905-1029-0100 100 µg 443.00 USD
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Product Specification

Alternative Name:Transmembrane protease serine 3, TADG-12
Immunogen:Recombinant protein corresponding to aa 221-317 of human TMPRSS3.
UniProt ID:P57727
Gene/Protein Identifier:64699 (Gene ID)
Species reactivity:Human
Applications:ELISA, WB
Purity Detail:Protein G-affinity purified.
Formulation:Liquid. In 1X PBS, pH 7.4, containing 10% glycerol and 0.05% sodium azide.
Shipping:Shipped on Blue Ice
Long Term Storage:-20°C
Scientific Background:This protein belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This protein was identified by its association with both congenital and childhood onset autosomal recessive deafness. This protein is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This protein was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Regulatory Status:RUO - Research Use Only

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