| ADI-905-1013-0100 | 100 µg | 431.00 USD |  |
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| Alternative Name: | Matrix metalloproteinase 7, Matrilysin |
| Clone: | 2D3 |
| Host: | Mouse |
| Isotype: | IgG |
| Immunogen: | Recombinant protein corresponding to aa 18-267 of human MMP-7 (His-tagged). |
| UniProt ID: | P09237 |
| Gene/Protein Identifier: | 4316 (Gene ID) |
| Species reactivity: | Human |
| Applications: | ELISA, WB |
| Application Notes: | Detects a band of ~29kDa by Western blot. |
| Purity Detail: | Protein G-affinity purified. |
| Formulation: | Liquid. In 1X PBS, pH 7.4, containing 10% glycerol and 0.05% sodium azide. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | MMP-7 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The MMP-7 enzyme degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
| Regulatory Status: | RUO - Research Use Only |
Matrix Metalloproteinase-7 (MMP-7) colorimetric drug discovery kit |
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| Colorimetric detection, HTS, Activity assay | Print as PDF | ||||||
| BML-AK406-0001 | 96 wells | 532.00 USD | |
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Matrix Metalloproteinase-7 (MMP-7) fluorometric drug discovery kit |
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| Fluorescent detection, HTS, Activity assay | Print as PDF | ||||||
| BML-AK407-0001 | 96 wells | 536.00 USD | |
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Matrix metalloproteinase-7 (MMP-7) fluorometric drug discovery kit, RED |
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| Fluorescent detection, HTS, Activity assay | Print as PDF | ||||||
| BML-AK304-0001 | 96 wells | 586.00 USD | |
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MMP-7 (catalytic domain) (human), (recombinant) |
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| Produced in E. coli. Active Matrix Metalloproteinase-7 (MMP-7, matrilysin, pump) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-7 (Tyr95-Lys267, NM_002423) with a C-terminal purification tag., ≥95% (SDS-PAGE) | Print as PDF | ||||||
| BML-SE181-0010 | 10 µg | 416.00 USD | |
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MMP-7 (CT) polyclonal antibody |
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| ELISA, IP, WB | Print as PDF | ||||||
| BML-SA625-0050 | 50 µg | 338.00 USD | |
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MMP-7 (human), immunoblotting standard |
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| Produced in E. coli. , WB | Print as PDF | ||||||
| BML-SW119-0300 | 300 µl | 131.00 USD | |
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