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Ready-to-use - liquid color-coded reagents reduce error
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Sensitive - detect < 4 pg/ml of IL-10
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Fast - results in < 3 hours from up to 39 samples in duplicate
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Ready-to-use reagents and pre-coated plates reduce errors and save your time
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Save with bulk kit package!
The IL-10 (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in < 3 hours. Absorbance is read at 450 nm. Ready-to-use liquid color-coded reagents reduce laboratory errors.
Product Details
| Alternative Name: | Interleukin-10 |
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| Sensitivity: | 3.75 pg/ml (range 7.81 - 500 pg/ml) |
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| Assay Time: | <3 hours |
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| Applications: | ELISA, Colorimetric detection
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| Application Notes: | For the quantitative determination of human IL-10 in culture supernatants, plasma, and serum. |
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| Wavelength: | 450 nm |
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| Species reactivity: | Human
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| Use/Stability: | Store all components at +4°C, except standard at -20°C. |
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| Shipping: | Blue Ice |
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| Contents: | Microtiter plate, Conjugate, Antibody, Assay buffer 13 concentrate, Wash buffer concentrate, Standard, TMB Substrate, Stop solution 2 |
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| Scientific Background: | Interleukin-10 (IL-10) was initially identified as the Cytokine Synthesis Inhibitory Factor based on the observation that mouse Th1 cytokine production was suppressed by a Th2-derived factor. IL-10 is a macrophage deactivating factor, acting on macrophage-monocyte accessory cells to produce its inhibitory effects on T cells and natural killer cells. It also regulates growth and/or differentiation of B cells, mast cells, granulocytes, dendritic cells, keratinocytes and endothelial cells. Circulating levels of IL-10 are increased in allergic asthma, systemic sclerosis, a variety of cancers, post-transplantation patients, and in sepsis. The therapeutic potential of IL-10 includes rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and HIV infection. |
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| Technical Info/Product Notes: | Cited samples:
Cytokine ELISAs Cited Samples |
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| UniProt ID: | P22301 |
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| Regulatory Status: | RUO - Research Use Only |
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| Compatibility: | This product is compatible with the Absorbance 96 Plate Reader.
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Product Literature References
Biflavonoid quercetin protects against cyclophosphamide–induced organ toxicities via modulation of inflammatory cytokines, brain neurotransmitters, and astrocyte immunoreactivity: A.Y. Onaolapo, et al.; Food Chem. Toxicol.
178, 113879 (2023),
Abstract;
Inflammatory and oxidative stress markers in intracerebral hemorrhage: Relevance as prognostic markers for quantification of the edema volume: V. Rendevski, et al.; Brain Pathol.
33, e13106 (2023),
Abstract;
Full Text
Exosomal circSHKBP1 participates in non-small cell lung cancer progression through PKM2-mediated glycolysis: W. Chen, et al.; Mol. Ther. Oncolytics
24, 470 (2022),
Abstract;
Effects of photobiomodulation and a physical exercise program on the expression of inflammatory and cartilage degradation biomarkers and functional capacity in women with knee osteoarthritis: a randomized blinded study: P.G. Vassão, et al.; Adv. Rheumatol.
61, 62 (2021),
Abstract;
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