- Rapid – results in just 3 hours from up to 40 samples in duplicate
- Convenient – user-friendly alternative to mass spectrometry
- Easy-to-use – simple procedure, liquid color-coded reagents and pre-coated plates to reduce error
- Quantitative – fully quantitative results surpass semi-quantitative Western blot analysis
- Sensitive – measure as little as 1 ng/ml of matriptase
The Matriptase ELISA kit is a complete, colorimetric, immunometric immunoassay kit for the quantitative determination of matriptase in plasma and serum with results in just 3 hours.
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Product Details
| Alternative Name: | TADG-15, ST14 |
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| Sensitivity: | 1 ng/ml (range 5-280 ng/ml) |
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| Assay Time: | ~3 hours |
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| Applications: | ELISA, Colorimetric detection
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| Application Notes: | For the quantitative determination of human matriptase in plasma and serum. |
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| Wavelength: | 450 nm |
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| Species reactivity: | Human
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| Crossreactivity: | No cross-reactivity with other serine proteases was detected for this assay. |
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| Use/Stability: | Store all components at +4°C |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Contents: | Microtiter Plate, Standards, Calibrators, Antibody-conjugate, Streptavidin-HRP, TMB Reagent, Stop Solution, Wash Buffer Concentrate |
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| Scientific Background: | The protein encoded by the Matriptase gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion and metastasis. |
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| UniProt ID: | Q9Y5Y6 |
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| GenBank ID: | 6647302 |
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| Gene/Protein Identifier: | 6768 (Gene ID) |
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| Regulatory Status: | RUO - Research Use Only |
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| Compatibility: | This product is compatible with the Absorbance 96 Plate Reader.
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