- Rapid – results in just 3 hours from up to 40 samples in duplicate
- Convenient – user-friendly alternative to mass spectrometry
- Easy-to-use – simple procedure, liquid color-coded reagents and pre-coated plates to reduce error
- Quantitative – fully quantitative results surpass semi-quantitative Western blot analysis
- Sensitive – measure as little as 1 ng/ml of kallikrein-6
The Kallikrein-6 ELISA kit is a complete, colorimetric, immunometric immunoassay kit for the quantitative determination of kallikrein-6 in serum with results in just 3 hours.
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Product Specification
| Alternative Name: | KLK6, Neurosin, Protease M |
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| Sensitivity: | 1 ng/ml (range 5-280 ng/ml) |
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| Assay Time: | ~3 hours |
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| Applications: | ELISA, Colorimetric detection
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| Application Notes: | For the quantitative determination of human kallikrein-6 in serum. |
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| Species reactivity: | Human
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| Crossreactivity: | No cross-reactivity with other serine proteases was detected for this assay. |
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| Use/Stability: | Store all components at +4°C |
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Contents: | Microtiter Plate, Standards, Calibrators, Antibody-conjugate, Streptavidin-HRP, TMB Substrate, Stop Solution, Wash Buffer Concentrate |
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| Scientific Background: | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins, including kallikrein-6 (KLK6), are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded KLK6 enzyme is regulated by steroid hormones. In tissue culture, KLK6 has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. |
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| UniProt ID: | Q92876 |
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| GenBank ID: | 30582543 |
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| Gene/Protein Identifier: | 5653 (Gene ID) |
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| Regulatory Status: | RUO - Research Use Only |
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