Rapid – results in just 3 hours from up to 40 samples in duplicate
Convenient – user-friendly alternative to mass spectrometry
Easy-to-use – simple procedure, liquid color-coded reagents and pre-coated plates to reduce error
Quantitative – fully quantitative results surpass semi-quantitative Western blot analysis
Sensitive – measure as little as 1 ng/ml of kallikrein-6
The Kallikrein-6 ELISA kit is a complete, colorimetric, immunometric immunoassay kit for the quantitative determination of kallikrein-6 in serum with results in just 3 hours.
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Product Specification
Alternative Name:
KLK6, Neurosin, Protease M
Sensitivity:
1 ng/ml (range 5-280 ng/ml)
Assay Time:
~3 hours
Applications:
ELISA, Colorimetric detection
Application Notes:
For the quantitative determination of human kallikrein-6 in serum.
Species reactivity:
Human
Crossreactivity:
No cross-reactivity with other serine proteases was detected for this assay.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins, including kallikrein-6 (KLK6), are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded KLK6 enzyme is regulated by steroid hormones. In tissue culture, KLK6 has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
Produced in insect cells. Human recombinant KLK6 (aa 17-244) is fused to a His-tag. Produced in a baculovirus expression system., ≥90% (SDS-PAGE), ELISA, WB | Print as PDF
