Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Dkk-1 (human), ELISA kit

First-to-market Dkk-1 ELISA commercially available for wnt signaling pathway research.
ADI-900-151 96 wells 435.00 USD
Do you need bulk/larger quantities?
  • Easy-to-use - ready-to-use liquid color-coded reagents reduce errors
  • Higher throughput - reproducible results from up to 39 samples in duplicate in just 3 hours
  • Trusted - validated with pathological and non-pathological samples
The Dkk-1 (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours. Absorbance is read at 450 nm. The Dkk-1 (human), EIA kit offers ultra-sensitive and accurate measurement of Dickkopf-1 and has been validated in-house in normal and pathological samples.
Dkk-1 (human), ELISA kit Kit graph
Please mouse over
Dkk-1 (human), ELISA kit Kit graph

Product Details

Alternative Name:Dickkopf-1
Sensitivity:0.98 pg/ml (range 7.81-500 pg/ml)
Assay Time:3 hours
Applications:ELISA, Colorimetric detection
Application Notes:For the quantitative determination of human Dkk-1 in culture supernatants, plasma, and serum.
Wavelength:450 nm
Species reactivity:Human
Use/Stability:Store all components at 4°C, except standard at -20°C.
Shipping:Shipped on Blue Ice
Contents:Microtiter plate, Conjugate, Antibody, Assay buffer 10 Concnetrate, Wash buffer concentrate, Standard, TMB Substrate, Stop solution 2
Scientific Background:Dkk-1 (Dickkopf-1) is a secreted inhibitor of the canonical Wnt signaling pathway, which mediates a variety of cellular processes including the growth and development of osteoblasts. Dkk-1 disrupts the canonical pathway by binding to the LRP5/6 co-receptors, preventing interaction with Wnt, and facilitating the degradation of beta-catenin. Dkk-1 is overexpressed in multiple myeloma, increasing bone resorption and the appearance of osteolytic lesions characteristic of multiple myeloma.
UniProt ID:O94907
Regulatory Status:RUO - Research Use Only
Compatibility:This product is compatible with the Absorbance 96 Plate Reader.

Plate Reader Just Got Personal

Product Literature References

Fewer bone disease events, improvement in bone remodeling, and evidence of bone healing with bortezomib plus melphalan-prednisone vs. melphalan-prednisone in the phase III VISTA trial in multiple myeloma: M. Delforge, et al.; Eur. J. Haematol. 86, 372 (2011), Application(s): EIA using human serum, Abstract;
Lack of diagnostic potential of Dickkopf-1 in colon and rectum cancers: H.O. Soydinc, et al.; Asian Pac. J. Cancer. Prev. 12, 3187 (2011), Application(s): EIA using human serum, Abstract; Full Text
The application of target information and preclinical pharmacokinetic/pharmacodynamic modeling in predicting clinical doses of a Dickkopf-1 antibody for osteoporosis: A.M. Betts, et al.; J. Pharmacol. Exp. Ther. 333, 2 (2010), Application(s): EIA using human serum, Abstract; Full Text

Related Products

Absorbance 96 Plate Reader 

Personal, Compact Plate Reader
ELISA, Colorimetric detection | Print as PDF
ENZ-INS-A96 1 ea Inquire for pricing

Related Literature

Integrated solutions for screening Wnt regulators
Integrated solutions for screening Wnt regulators
Download as PDF

Stem Cells
Stem Cells
Download as PDF

Immunoassay Kits
Immunoassay Kits
Download as PDF

All new literature pieces

Recommend this page

Keep in touch

©2021 Enzo Life Sciences, Inc.,