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XIAP (human), ELISA kit



ADI-900-124	96 wells	Inquire for pricing
Do you need bulk/larger quantities?

Convenient - pre-coated plates and liquid color-coded reagents reduce errors
Quantitative - save time and achieve fully quantitative results compared to semi-quantitative Western blot analysis
Specific - no reactivity with structurally related molecules

The XIAP (human), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 3 hours. Absorbance is read at 450 nm. Save time, money, and precious sample with fully quantitative results and increased sensitivity compared to Western blot analysis.

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Product Specification

Alternative Name:	X-linked inhibitor of apoptosis

Sensitivity:	90.6 pg/ml (range 312.5 - 10,000 pg/ml)

Assay Time:	3 hours

Applications:	ELISA, Colorimetric detection

Application Notes:	For the quantitative determination of human XIAP in cell lysates.

Species reactivity:	Human

Crossreactivity:	Human XIAP (100%), Survivin (3.2%) and <0.1%: cIAP-1, Caspase-3, Smac, DIABLO

Use/Stability:	Store all components at 4°C, except standard at -20°C.

Shipping:	Shipped on Blue Ice

Contents:	Microtiter plate, Conjugate, Antibody, Assay buffer 21, RIPA Cell lysis buffer 2, Wash buffer concentrate, Standard, TMB Substrate, Stop solution 2

Scientific Background:	XIAP (X-linked inhibitor of apoptosis) belongs to the IAP (inhibitors of apoptosis) family, which is characterized by one or more BIR (baculovirus IAP repeat) domains. These proteins have multiple biological functions that include binding and inhibiting caspases, regulating cell cycle progression, and modulating receptor-mediated signal transduction. XIAP functions by direct binding and inhibition of several caspases, including caspase-3, caspase-7 and caspase-9.

UniProt ID:	P98170

Regulatory Status:	RUO - Research Use Only

Compatibility:	This product is compatible with the Absorbance 96 Plate Reader.

Product Literature References

The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells: H. Kauntz, et al.; Apoptosis 17, 797 (2012), Application(s): ELISA using cell lysates, Abstract;