- Fast - fully quantitative results in just 2 hours
- Sensitive - measure < 21 pg/ml MCP-1
- Higher throughput - test up to 40 samples in duplicate
The MCP-1 (rat), EIA kit is a colorimetric immunometric enzyme immunoassay kit with results in 2 hours. Absorbance is read at 450 nm.
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Product Details
| Alternative Name: | Monocyte chemoattractant protein 1 |
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| Sensitivity: | 20.45 pg/ml (range 50 - 3,200 pg/ml) |
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| Assay Time: | 2 hours |
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| Applications: | ELISA, Colorimetric detection
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| Application Notes: | For the quantitative determination of rat MCP-1 in culture supernatants and serum. |
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| Wavelength: | 450 nm |
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| Species reactivity: | Rat
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| Shipping: | Blue Ice Not Frozen |
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| Long Term Storage: | +4°C |
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| Contents: | Microtiter plate, Labeled antibody concentrate, Antibody diluent, Assay buffer, Wash buffer concentrate, Standard, TMB Substrate, Stop solution |
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| Scientific Background: | Monocyte chemoattractant protein-1 (MCP-1) is a 76 amino acid protein that belongs to the family of chemotactic cytokines (CC). MCP-1 is highly chemotactic for monocytes, T lymphocytes, basophils, and NK cells during inflammatory responses. MCP-1 is synthesized by a wide variety of cell types including monocytes and vascular endothelial and smooth muscle cells, and is also known to regulate adhesion molecule expression and cytokine production in monocytes. Overexpression of MCP-1 has been associated with rheumatoid arthritis, atherosclerosis, melanoma, invasive breast cancer, and the promotion of angiogenesis. |
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| Technical Info/Product Notes: | Cited samples:
Cytokine ELISAs Cited Samples |
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| UniProt ID: | P14844 |
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| Regulatory Status: | RUO - Research Use Only |
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| Compatibility: | This product is compatible with the Absorbance 96 Plate Reader.
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Product Literature References
Renoprotective effects of montelukast in an experimental model of cisplatin nephrotoxicity in rats: A.M. Gad, et al.; J. Biochem. Mol. Toxicol.
31, (2017),
Application(s): Rat serum and renal lysates,
Abstract;
The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity: B. Shan, et al.; Nat. Immunol.
18, 519 (2017),
Abstract;
Chronic inflammation: is it the driver or is it paving the road for malignant transformation?: K. Afrasiabi, et al.; Genes Cancer
6, 214 (2015),
Application(s): ELISA,
Abstract;
Full Text
Ellagic acid antiinflammatory and antiapoptotic potential mediate renoprotection in cisplatin nephrotoxic rats: A.M. El-Garhy, et al.; J. Biochem. Mol. Toxicol.
28, 472 (2014),
Application(s): Rat serum and renal lysates,
Abstract;
Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats: S. Li, et al.; PLoS One
9, e86724 (2014),
Application(s): ELISA using rat serum,
Abstract;
Full Text
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