A distinctive combination of reagents comprised of exceptional fluorescent molecular probes including CELLESTIAL® dyes for live, fixed and permeabilized cells. Products for drug discovery and research, in dynamic intracellular analysis with high spatial and temporal resolution for target, pathway and cell signaling analysis, reactive oxygen and reactive nitrogen species (ROS/RNS) detection, apoptosis and cell viability, and organelle functional dynamics.
The use of fluorescent dyes to identify cell structural components and monitor cytotoxicity or cellular responses to growth signals is well established. In addition to a wide selection of gold standard labeling dyes such as DAPI, Hoechst, and JC-1, Enzo Life Sciences has translated its expertise in fluorescent probe chemistry and cellular analysis into our CELLestial® portfolio of unique probe-based assays and reagents to meet the emerging needs of the life sciences and drug discovery markets. From simple organelle specific dyes for imaging cell structure and determining cell viability, to more complex dyes and reporter assays for monitoring cell signaling, death pathways, and toxicity, every product is developed and reliably manufactured to provide sensitivity, specificity, and convenience.
Cell Death & AutophagyNo-transfection assays for detecting apoptosis, necrosis and autophagy. |
Cell Function & ViabilityHigh-performance dyes for cell cycle analysis, calcium mobilization, cell lineage tracing, and more. |
Drug Safety & Toxicology
Consistent and economical dyes for in vitro toxicology assays. |
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Cell Structure & Organelle DetectionMulti-color organelle-specific dyes for co-localization studies and monitoring changes in cell structure. |
Oxidative StressMonitor Oxidative Stress with Sensitive Assays for Mitochondrial Membrane Potential and accumulation of Reactive Oxygen Species (ROS). |
Conventional fluorescent dyes for organelle detection & function including DAPI, Hoechst, JC-1, and more.
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Ion Detection
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Cellular Staining
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Cell Viability
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Reactive Dyes and Stains
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EQ quencher dyes are suitable as acceptors in fluorescence resonance energy transfer (FRET) applications due to their broad visible absorption but no detectable fluorescence emission.
Normalized absorbance of EQ dyes showing their range of quenching through FRET.
Flow cytometry allows researchers to measure several physical characteristics of cells including its shape, size, and internal complexity. It has long been used in cell counting and cell sorting but more recently, researchers have been using flow cytometry in a broad range of applications including: biomarker detection, cell signaling, pathway screening, protein engineering, and systems biology. Flow cytometry is inherently a robust technique that adapts easily to basic research, drug development, and diagnostics.
Enzo Life Sciences offers a variety of flow cytometry-based assays for cell viability, proliferation and death analysis, available in a wide range of formats to meet individual research needs. We also offer unique flow cytometry-based assays to measure oxidative stress and to profile multi-drug resistance. These flexible assays are compatible with all flow cytometry platforms, regardless of size or functionality. The assays are easy to perform and can be run quickly using small sample input, without sacrificing sensitivity.
In addition, Enzo Life Sciences offers more than 600 antibodies that have been validated for flow cytometry. These include isotype controls as well as biotin and fluorescent conjugates for use in evaluating intracellular and extracellular proteins.
