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2009 Proteostasis References

  • A kinetic assessment of the C. elegans amyloid disaggregation activity enables uncoupling of disassembly and proteolysis. Protein Sci. 2009, PubMed
  • A small molecule inhibitor of inducible heat shock protein 70. Mol.Cell 2009, PubMed
  • Angelman syndrome scientific symposium on the structure and function of UBE3A/E6AP. J.Child Neurol. 2009, PubMed
  • Autophagy and ethanol-induced liver injury. World J.Gastroenterol. 2009, PubMed
  • Biological and chemical approaches to diseases of proteostasis deficiency. Annu.Rev.Biochem. 2009, PubMed
  • Cell-type-specific differentiation of chloroplasts in C4 plants. Trends Plant Sci. 2009, PubMed
  • Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging. Proc.Natl.Acad.Sci.U.S.A 2009, PubMed
  • Creutzfeldt-jakob, Parkinson, lewy body dementia and Alzheimer diseases: from diagnosis to therapy. Cent.Nerv.Syst.Agents Med.Chem. 2009, PubMed
  • Developmental changes in the concentrations of glutamine and other amino acids in plasma and skeletal muscle of the Standardbred foal. J.Anim Sci. 2009, PubMed
  • Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates. PLoS.Genet. 2009, PubMed
  • Endoplasmic reticulum stress in the kidney as a novel mediator of kidney injury. Nephron Exp.Nephrol. 2009, PubMed
  • Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J.Cell Biol. 2009, PubMed
  • Identification of biomarkers indicating cellular changes after treatment of neuronal cells with the C3 exoenzyme from Clostridium botulinum using the iTRAQ protocol and LC-MS/MS analysis. J.Chromatogr.B Analyt.Technol.Biomed.Life Sci. 2009, PubMed
  • Inhibiting the transcription factor HSF1 as an anticancer strategy. Expert.Opin.Ther.Targets. 2009, PubMed
  • Integrating the stress response: lessons for neurodegenerative diseases from C. elegans. Trends Cell Biol. 2009, PubMed
  • Large scale comparative proteomics of a chloroplast Clp protease mutant reveals folding stress, altered protein homeostasis, and feedback regulation of metabolism. Mol.Cell Proteomics. 2009, PubMed
  • Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein. Am.J.Pathol. 2009, PubMed
  • Modulating proteostasis: peptidomimetic inhibitors and activators of protein folding. Curr.Pharm.Des 2009, PubMed
  • Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. AAPS.J. 2009, PubMed
  • Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins. Proc.Natl.Acad.Sci.U.S.A 2009, PubMed
  • Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination. J.Mol.Biol. 2009, PubMed
  • Protein homeostasis and aging: taking care of proteins from the cradle to the grave. J.Gerontol.A Biol.Sci.Med.Sci. 2009, PubMed
  • Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3. EMBO J. 2009, PubMed
  • Quantitative approaches to defining normal and aberrant protein homeostasis. Faraday Discuss. 2009, PubMed
  • Secretion of amyloidogenic gelsolin progressively compromises protein homeostasis leading to the intracellular aggregation of proteins. Proc.Natl.Acad.Sci.U.S.A 2009, PubMed
  • Small-molecule modulation of cellular chaperones to treat protein misfolding disorders. Curr.Opin.Drug Discov.Devel. 2009, PubMed
  • Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 2009, PubMed
  • Subunits of the plastid ClpPR protease complex have differential contributions to embryogenesis, plastid biogenesis, and plant development in Arabidopsis. Plant Cell 2009, PubMed
  • Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 2009, PubMed
  • The long lifespan of two bat species is correlated with resistance to protein oxidation and enhanced protein homeostasis. FASEB J. 2009, PubMed
  • The proteostasis boundary in misfolding diseases of membrane traffic. FEBS Lett. 2009, PubMed

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