Tutorial: Heat Shock Proteins and the Stress Response

HSPs [HSP90, HSP70/40, HSP60/10, GroEL/ES & more]
Heme Oxygenases
Small HSPs [Crystallin, HSP20, HSP25, HSP27 & more]
Co-Chaperones & HSP-interacting Proteins
HSF
Mitochondrial HSPs [Mortalin, Grp75]
ER Stress [ERp57, ERp72, Grp94, Calnexin, Calnexin & more]
Neurodegenerative Diseases
Clusterin
More Stress & HSPs

All Stress & HSPs

A tutorial covering the principal heat shock protein families with a focus on their structure, function, cellular localization, and their role in key cellular stress responses and disease states such as cancer.

Part I: Heat shock proteins (Hsps)

• Background
  
• Naming and organization
  
• Families and isotypes
  
• Function
  
• Localization
  
• Stress conditions/disease

Part II: Specific families with focus on their family members, function, structure,

• Hsp70/40 complex
  
• Hsp90 and its co-chaperones
  
• Hsp60/10 chaperonin complex
  
• Small Hsp family (sHsp)