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Tutorial: Heat Shock Proteins and the Stress Response

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HSPs [HSP90, HSP70/40, HSP60/10, GroEL/ES & more]
Heme Oxygenases
Small HSPs [Crystallin, HSP20, HSP25, HSP27 & more]
Co-Chaperones & HSP-interacting Proteins
HSF
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ER Stress [ERp57, ERp72, Grp94, Calnexin, Calnexin & more]
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A tutorial covering the principal heat shock protein families with a focus on their structure, function, cellular localization, and their role in key cellular stress responses and disease states such as cancer.

Part I: Heat shock proteins (Hsps)

  • Background
  • Naming and organization
  • Families and isotypes
  • Function
  • Localization
  • Stress conditions/disease


Part II: Specific families with focus on their family members, function, structure,

  • Hsp70/40 complex
  • Hsp90 and its co-chaperones
  • Hsp60/10 chaperonin complex
  • Small Hsp family (sHsp)
 

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For Research Use Only. Not for use in diagnostic procedures.
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