United States
Cellestial Assays for In Vitro Toxicology
Our panel of fluorescence-based live cell assays are designed to help assess the impact of toxic agents on overall cell function. Our assays and probes have been developed to produce dyes that are sensitive, specific, and convenient, offering increased photostability, eliminating non-specific dye-associated artifacts to reduce false positives, and compatibility with common dyes and fluorescent markers for multiplex analysis. Our dyes are optimized for the most demanding imaging applications, including microplate-based high content screening, flow cytometry, confocal microscopy, and wide-field fluorescence microscopy, where consistency and reproducibility are essential.
Cell Death Pathways
Quantify Autophagy. Apoptosis, and Necrosis with sensitive, multiplex-amenable dyes.
Aggresome Accumulation
ProteoStat® Aggresome Detection Kit is the only assay that detects aggresomes and aggresome-like inclusion bodies by imaging and flow cytometry.
Oxidative Stress
Monitor Oxidative Stress with Sensitive Assays for Mitochondrial Membrane Potential and accumulation of Reactive Oxygen Species (ROS).
Lysosome Perturbations
Lyso-ID® Red Cytotoxicity Assay is the only commercial assay available for long-term monitoring of phospholipidosis and generalized cytotoxicity. HTS compatible with rapid 10-15 minute dye incubation.
Multidrug Resistance
eFluxx-ID™ Multidrug Resistance Assay Kits are the only available kits for simultaneous monitoring of all three major ABC transporter proteins — MDR, MRP & BCRP.
