Online Purchasing Account You are logged on as Guest. LoginRegister a New AccountShopping cart (Empty)
United States 

Water Bears: Survival Of The Fittest

Tardigrades (water bears) are microscopic aquatic animals found in various habitats such as marine, fresh water or moist terrestrial environments. Surprisingly, water bears can survive extreme conditions such as boiling and freezing temperatures, high pressure, rapid dehydration, starvation and large doses of radiation. They have even survived in outer space. The R. varieorantus genome was sequenced to understand the molecular mechanisms that enable exceptional tolerance to harsh environments.

A recent study identified the Dsup (Damage suppression) gene that protects DNA from radiation. The Dsup protein can also prevent and repair damage from reactive oxygen species (ROS). High levels of ROS can cause significant damage to cell structures and can lead to aging and cancer. Researchers inserted Dsup into human cells and exposed them to X-rays. This unique protein confers an ability to tolerate large doses of radiation that would usually kill other animals. Significantly less damage (40-50%) was seen in the cells containing the modified genetic material. These findings indicate the significance of sequencing genomes. Identifying proteins that provide protection from extreme conditions will be highly beneficial. This research offers clues into stress tolerance and the limits of cells. Could similar DNA protection be passed on to plants, humans and animals? Crops could be cultivated in harsh environments while humans and other animals could possibly become radiation resistant that is helpful to people undergoing radiotherapy and even space flight.

For more information: http://www.nature.com/ncomms/2016/160920/ncomms12808/full/ncomms12808.html

Enzo Life Sciences provides a wide variety of products for your Cellular Analysis platform. Our product portfolio provides kits, probes, reagents and libraries for your Oxidative Stress research needs. We offer a highly sensitive ROS-ID® Total ROS/Superoxide detection kit that can directly monitor global levels of ROS with high specificity and accuracy for live cell studies.

Never miss a new TechNote!

Receive our TechNotes as soon as they are published.


 
comments powered by Disqus

follow Us!

 

Related Products

ROS-ID® NO Detection kit 

Fluorescence microscopy, Fluorescent detection | Print as PDF
 
ENZ-51013-200 1 Kit 175.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® ROS/RNS detection kit 

Monitor  reactive oxygen species and nitrogen species in live cells
Fluorescence microscopy | Print as PDF
 
ENZ-51001-200 1 Kit 287.00 USD
Do you need bulk/larger quantities?
 

DNA damage ELISA kit 

Rapid DNA damage ELISA kit for cancer, apoptosis and oxidative stress.
ELISA, Colorimetric detection | Print as PDF
 
ADI-EKS-350 96 wells 750.00 USD
Do you need bulk/larger quantities?
 

Nitric Oxide (total), detection kit 

Colorimetric detection | Print as PDF
 
ADI-917-020 2x96 wells 246.00 USD
Do you need bulk/larger quantities?
 

Nitric Oxide (NO2-/NO3-) detection kit 

Colorimetric detection | Print as PDF
 
ADI-917-010 2x96 wells 248.00 USD
Do you need bulk/larger quantities?
 

ROS-ID® Total ROS detection kit 

Flow Cytometry, Fluorescence microscopy, Fluorescent detection, HTS | Print as PDF
 
ENZ-51011 1 Kit 175.00 USD
Do you need bulk/larger quantities?
 

SCREEN-WELL® REDOX library 

HTS | Print as PDF
 
BML-2835-0500 1 Library 500 µl/well Inquire for pricing
 
BML-2835-0100 1 Library 100 µl/well Inquire for pricing
Do you need bulk/larger quantities?
 

APF 

Fluorescent probe for hROS detection
359010-70-1, ≥98% (HPLC) | Print as PDF
 
ALX-620-075-M001 1 mg 530.00 USD
Do you need bulk/larger quantities?
 

DMNQ 

Inducer of intracellular ROS generation
6956-96-3, ≥99% (TLC) | Print as PDF
 
ALX-420-027-M005 5 mg 87.00 USD
 
ALX-420-027-M010 10 mg 131.00 USD
 
ALX-420-027-M025 25 mg 285.00 USD
Do you need bulk/larger quantities?
 

4-Amino-TEMPO, free radical 

14691-88-4, ≥97% (HPLC) | Print as PDF
 
ALX-400-019-M010 10 mg 10.00 USD
 
ALX-400-019-M050 50 mg 34.00 USD
Do you need bulk/larger quantities?
 

Galvinoxyl, free radical 

2370-18-5, ≥95% (TLC) | Print as PDF
 
ALX-400-016-M010 10 mg 10.00 USD
 
ALX-400-016-M050 50 mg 31.00 USD
Do you need bulk/larger quantities?
 

Recommend this page

 
For Research Use Only. Not for use in diagnostic procedures.
Keep in touch

©2018 Enzo Life Sciences, Inc.,