Cancer stem cells (CSC) are tumor forming and found within most cancers including breast, colon, prostate, melanoma, ovary and pancreatic. These cells can undergo self-renewal and differentiate into multiple cell types that lead to tumor generation. CSCs make up a small subpopulation of cells found in tumors and are the main cause of relapse and metastasis in cancer patients. Existing cancer treatments have been developed on animal research models. However, tumor relapse is hard to study using animal models, and CSCs are typically slow growing and drug resistant. Often, that leads to evasion of traditional cancer therapies. Therefore, development of specific therapeutics to target CSCs is essential for improving cancer survival rates and for treatment of more aggressive, non-resectable tumors.
Tags: Cancer, Epigenetics, In The News
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SCREEN-WELL® Epigenetics library |
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| HTS | Print as PDF | ||||||
| BML-2836-0100 | 1 Library | 100 µl/well | 1,372.00 USD |  |
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| BML-2836-0500 | 1 Library | 500 µl/well | 4,654.00 USD | |
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FLUOR DE LYS® HDAC fluorometric activity assay kit |
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| First-to-market by the leader in Epigenetics research tools | ||||||
| Fluorescent detection, HTS, Activity assay | Print as PDF | ||||||
| BML-AK500-0001 | 96 wells | 638.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
FLUOR DE LYS® HDAC fluorometric cellular activity assay kit |
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| Monitor HDAC activity in cell culture using cell-permeable FLUOR DE LYS® substrate | ||||||
| Fluorescent detection, HTS, Activity assay, Cell-based assays | Print as PDF | ||||||
| BML-AK503-0001 | 96 wells | 587.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
FLUOR DE LYS® SIRT5 fluorometric drug discovery assay kit |
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| A Sensitive Fluorometric Assay for Screening SIRT5 Inhibitors | ||||||
| Fluorescent detection, HTS, Activity assay, Cell-based assays | Print as PDF | ||||||
| BML-AK513-0001 | 100 tests | 814.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
FLUOR DE LYS® Green SIRT5 fluorometric drug discovery assay kit |
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| A Sensitive Fluorometric Assay for Screening SIRT5 Inhibitors | ||||||
| Fluorescent detection, HTS, Activity assay, Cell-based assays | Print as PDF | ||||||
| BML-AK514-0001 | 100 tests | 790.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
FLUOR DE LYS®-Green HDAC fluorometric activity assay kit |
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| Fluorescent detection, HTS, Activity assay, Cell-based assays | Print as PDF | ||||||
| BML-AK530-0001 | 96 wells | Inquire for pricing | ||||
| Do you need bulk/larger quantities? | ||||||
FLUOR DE LYS® SIRT1 fluorometric drug discovery assay kit |
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| First-to-market by the leader in Epigenetics research tools | ||||||
| Fluorescent detection, HTS, Activity assay, Cell-based assays | Print as PDF | ||||||
| BML-AK555-0001 | 96 wells | 849.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
FLUOR DE LYS® SIRT2 fluorometric drug discovery assay kit |
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| Fluorescent detection, HTS, Activity assay, Cell-based assays | Print as PDF | ||||||
| BML-AK556-0001 | 96 wells | 864.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
FLUOR DE LYS® SIRT3 fluorometric drug discovery assay kit |
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| Fluorescent detection, HTS, Activity assay, Cell-based assays | Print as PDF | ||||||
| BML-AK557-0001 | 96 wells | 849.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
CHEMILUM DE LYS® HDAC/SIRT Chemiluminescent drug discovery kit |
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| All the Benefits of Chemiluminescent Detection Without Any of the Side Effects | ||||||
| Chemiluminescence, HTS, Activity assay | Print as PDF | ||||||
| BML-AK532-0001 | 96 wells | 790.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
COLOR DE LYS® HDAC colorimetric activity assay kit |
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| Simplify HDAC activity analysis with the fastest colorimetric assay on the market | ||||||
| Colorimetric detection, HTS, Activity assay | Print as PDF | ||||||
| BML-AK501-0001 | 96 wells | 531.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
Resveratrol |
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| Antioxidant. SIRT1 activator. | ||||||
| 501-36-0, ≥98% (HPLC) | Print as PDF | ||||||
| BML-FR104-0100 | 100 mg | 73.00 USD | |
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| BML-FR104-0500 | 500 mg | 321.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
BML-281 |
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| HDAC6 inhibitor | ||||||
| 1045792-66-2, ≥98% (TLC) | Print as PDF | ||||||
| BML-GR361-0001 | 1 mg | 116.00 USD | |
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| BML-GR361-0005 | 5 mg | 463.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
Butein |
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| Tyrosine kinase inhibitor | ||||||
| 487-52-5, ≥98% (HPLC) | Print as PDF | ||||||
| ALX-350-246-M010 | 10 mg | 269.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
HDAC1 (human), (recombinant) (His-tag) |
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| Highly active | ||||||
| Produced in insect cells. HDAC1 from human cDNA (482 aa). Produced in a baculovirus expression system. | Print as PDF | ||||||
| BML-SE456-0050 | 50 µg | 569.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
HDAC2 (full-length) (human), (recombinant) (His-tag) |
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| Highly active | ||||||
| Produced in insect cells. Produced in a baculovirus expression system. | Print as PDF | ||||||
| BML-SE533-0050 | 50 µg | 569.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
HDAC3 (human), (recombinant) (His-tag) |
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| Highly active | ||||||
| Produced in insect cells. Produced in a baculovirus expression system. | Print as PDF | ||||||
| BML-SE507-0050 | 50 µg | 569.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
HAT activity assay kit |
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| Colorimetric detection, Activity assay | Print as PDF | ||||||
| ALX-850-326-KI01 | 100 tests | 758.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
Acetyltransferase activity kit |
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| Fluorescent detection, HTS, Activity assay | Print as PDF | ||||||
| ADI-907-026 | 96 wells | 591.00 USD | |
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| Do you need bulk/larger quantities? | ||||||
