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2019 April 15 | Tags: In The News

Researchers identified USP15, a deubiquitinating enzyme, as playing an important role in maintaining genome stability and tumor suppression. USP15 deletions occur in 16% of breast cancers and 5% of pancreatic cancers. The data suggest that cancer-linked USP15 mutations can increase poly ADP ribose polymerase (PARP) sensitivity in cancer cells Read More

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Our bi-weekly TechNotes are an easy way for you to keep in touch with how Enzo Life Sciences is living up to our motto: Scientists Enabling Scientists™. Each TechNote connects recently published research with one or more of the many solutions Enzo provides for scientists across the life sciences, drug development, and clinical research communities.

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2019 April 2 | Tags: In The News

Obesity is a risk factor for metabolic disorders including diabetes and cardiovascular disease. Atrial natriuretic peptide (ANP) and the related B-type NP (BNP) are synthesized in cardiac muscle cells in response to various forms of stress. They are key factors that act on the kidney to control blood pressure. ANP and BNP levels can be used as biomarkers to rule out myocardial infarction. Read More

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2019 March 29 | Tags: Cancer, Molecular Biology
2019 March 19 | Tags: In The News

There is growing evidence that alcohol and drug use can cause lasting genetic changes that may reinforce substance addiction that could also be passed down to future generations. Epigenetics focuses on how environmental factors can cause immediate genetic changes. DNA methylation is one epigenetic mechanism that is affected by external factors including environmental stress, chemical exposure, and disease. Read More

2019 March 3 | Tags: In The News

In a recent report, researchers have genetically engineered pluripotent stem cells using CRISPR-Cas9 gene editing to create cells that are invisible to the immune system. Newly altered stem cells with two deleted histocompatibility complex genes (MHC class I and II) and overexpression of the CD47 protein did not trigger an immune response. Read More

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