| Alternative Name: | NGR β1, HRG1β, Heregulin β1 |
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| MW: | ~ 7.6 kDa |
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| Source: | Produced in E. coli. A non-glycosylated protein containing 66 amino acids. |
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| UniProt ID: | Q02297-6 |
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| Formulation: | Lyophilized. Contains 0.1% trifluoroacetic acid. |
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| Purity: | ≥95% (SDS-PAGE) |
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| Endotoxin Content: | ≤0.05 EU/µg protein (LAL method) |
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| Reconstitution: | Reconstitute in sterile water at 0.1 mg/mL. |
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| Shipping: | Ambient Temperature |
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| Short Term Storage: | +4°C |
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| Long Term Storage: | -80°C |
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| Handling: | Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -80°C. For long term storage, it is recomended to dilute to working aliquots in a 0.1% BSA solution. |
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| Scientific Background: | Neuregulin 1-β (NRG1) is one of many NRG isoforms that contains a soluble EGF-like domain. The EGF-like domain signals through receptors ErbB2, ErbB3, and ErbB4 to act as a growth factor. NRG isoforms are important for nervous system and cardiovascular development. |
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| Regulatory Status: | RUO - Research Use Only |
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