Alternative Name: | IGPR-1, Transmembrane and immunoglobulin domain-containing protein 2, CD28H |
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Clone: | 8A1 |
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Host: | Mouse |
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Isotype: | IgG1κ |
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Immunogen: | Extracellular domain of human TMIGD2. |
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UniProt ID: | Q96BF3 |
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Species reactivity: | Human
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Applications: | Flow Cytometry, ICC, IF, IHC (PS), WB
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Purity Detail: | Protein A affinity purified. |
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Formulation: | Liquid. In PBS containing 0.02% sodium azide and 50% glycerol. |
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Use/Stability: | Stable for at least 1 year after receipt when stored as recommended. |
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Handling: | Avoid freeze/thaw cycles. |
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Shipping: | Blue Ice |
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Long Term Storage: | -20°C |
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Scientific Background: | TMIGD2 (transmembrane and immunoglobulin domain containing 1) is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins. TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration. |
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Regulatory Status: | RUO - Research Use Only |
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Western blot analysis of TMIGD2 in overexpressing HEK293 cells TMIGD2 antibody at 0.25, 0.5, and 1 µg/ml
Immunofluorescence of TMIGD2 in human colon carcinoma tissue with TMIGD2 antibody at 20 µg/mL.
Immunocytochemistry of TMIGD2 in transfected HEK293 cells with TMIGD2 antibody at 2 µg/mL. Lower left: Immunocytochemistry in transfected HEK293 cells with control mouse IgG antibody at 2 µg/mL.