| Alternative Name: | CgA, CHGA, Parathyroid secretory protein 1 |
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| Host: | Sheep |
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| Immunogen: | Synthetic peptide corresponding to aa 1-15 (L1PVNSPMNKGDTEVM15) of native human chromogranin A, conjugated to KLH. |
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| UniProt ID: | P10645 |
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| Species reactivity: | Human
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| Crossreactivity: | Expected reactivity due to sequence homology with bovine, chimpanzee, dog, horse, pig, mouse, rat. |
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| Applications: | ELISA, IHC
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| Formulation: | Liquid. In PBS containing 0.09% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Scientific Background: | Chromogranin A (CgA) is a prohormone which is proteolytically processed in neurons prior to axonal transport. The differential expression of chromogranin A fragments in neuronal populations suggests distinct functional roles for each CgA-derived peptide. Immunohistochemical localization of CgA has been used as a marker for the identification and prognostic assessment of neuroendocrine tumours and CgA has also been reported to be a component of senile plaques in the brains of demented individuals. |
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| Regulatory Status: | RUO - Research Use Only |
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