Product Details
| Alternative Name: | BRCA1-associated protein 1, Ubiquitin C-terminal hydrolase BAP1 |
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| MW: | 84.1 kDa |
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| Source: | Produced in E. coli. Human BAP1 is fused at the N-terminus to a His-tag. |
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| UniProt ID: | Q92560 |
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| Formulation: | Liquid. In 50mM Na-phosphate, pH 8.0, 300mM NaCl. |
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| Purity: | ≥90% (SDS-PAGE) |
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| Purity Detail: | Purified by Ni-affinity chromatography. |
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| Application Notes: | Uses:
Deubiquitinylation assays using small molecule substrates (e.g. Ub-AMC) or ubiquitin-protein conjugates.
Studies of the tumor suppressor BRCA1, its interactions and associated proteins. |
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | BAP1 is a BRCA1-associated ubiquitin C-terminal hydrolase. It shows homology to members of the ubiquitin C-terminal hydrolase (UCH) family and exhibits deubiquitinylating activity in vitro. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Spontaneous cellular and humoral tumor antigen responses in patients with uveal melanoma: P.L. Triozzi, et al.; Melanoma Res.
25, 510 (2015),
Application(s): Added to PBMC cell culture,
Abstract;
