Mature protein for functional studies.
Product Details
| Alternative Name: | Sentrin-2, Small ubiquitin-related modifier 2, SUMO-3 |
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| MW: | 15.4 kDa |
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| Source: | Produced in E. coli. Human SUMO-2 is fused to an N-terminal His-tag. |
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| UniProt ID: | P61956 |
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| Formulation: | Liquid. In 20mM HEPES, pH 8.0, containing 50mM NaCl, 1mM DTT. |
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| Application Notes: | Uses:
- SUMO-2 modification of specific proteins in vitro.
- Demonstrate novel proteins are potential targets for SUMOylation under in vitro conditions.
- Generate substrates for deSUMOylating enzymes.
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| Shipping: | Dry Ice |
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| Long Term Storage: | -80°C |
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| Scientific Background: | Conjugation of mature SUMO proteins to specific lysine residues on target proteins via isopeptide bonds, is involved in a range of processes including nuclear protein targeting, formation of sub-nuclear complexes, regulation of transcriptional activities, and control of protein stability. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
DEK oncoprotein participates in heterochromatin replication via SUMO-dependent nuclear bodies: A. Pierzynska-Mach, et al.; J. Cell Sci. (2023),
Abstract;
