His-Ubiquitin is activated by E1 and is a competent substrate for the E2 and E3 enzymes.
Product Details
| Source: | Produced in E. coli. |
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| UniProt ID: | P0CG47 (UBB), P0CG48 (UBC), P62979 (RPS27A), P62987 (UBA52) |
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| Formulation: | Liquid. In 50 mM Tris-buffered saline, pH 7.5. |
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| Application Notes: | Useful for studying ubiquitinylation in vitro and for the detection and purification of ubiquitinylated substrates. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis: Y. Fan, et al.; Cell Death Differ.
29, 1673 (2022),
Abstract;
ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer: K. Li, et al.; Cell Res.
30, 163 (2019),
Abstract;
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ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation: S. Wakatsuki, et al.; Nat. Cell Biol.
13, 1415 (2011),
Abstract;
