A proline-arginine-rich peptide antibiotic. PR39 inhibits DNA and protein synthesis and the degradation of HIF-1α. It has been reported to bind to the α7 subunit of the 26S proteasome, blocking degradation of the NK-κB inhibitor, IκBα by the ubiquitin-proteasome pathway without affecting overall proteasome activity. More recent studies have demonstrated it to be an efficient inhibitor of all activities of the 20S proteasome.
Product Details
| MW: | 4720.70 |
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| Purity: | ≥95% |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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