Product Details
| Alternative Name: | 26S protease regulatory subunit 6A, Tat-binding protein homolog 1, TBP-1 |
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| Host: | Rabbit |
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| Immunogen: | Recombinant protein corresponding to the N-terminal 100 amino acids of Yta1. |
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| UniProt ID: | P33297 |
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| GenBank ID: | 464859 |
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| Species reactivity: | Yeast
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| Specificity: | Recognizes the Rpt5/S6a subunit of the 19S regulator complex. |
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| Applications: | WB
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| Formulation: | Liquid. In PBS containing 10mM sodium azide. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Assembly chaperone Nas6 selectively destabilizes 26S proteasomes with defective regulatory particle-core particle interfaces: J.L. Warnock, et al.; J. Biol. Chem.
299, 102894 (2023),
Abstract;
Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones: A. Nahar, et al.; Cell Rep.
39, 110918 (2022),
Abstract;
Proteasome subunit α1 overexpression preferentially drives canonical proteasome biogenesis and enhances stress tolerance in yeast: L.A. Howell, et al.; Sci. Rep.
9, 12418 (2019),
Abstract;
Full Text
DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis: A. Nassrallah, et al.; Elife
7, e37892 (2018),
Abstract;
Full Text
An evolutionarily conserved pathway controls proteasome homeostasis: A. Rousseau, et al.; Nature
536, 184 (2016),
Abstract;
Full Text
Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation: W.H. Choi, et al.; Nat. Commun.
7, 10963 (2016),
Application(s): Western blot,
Abstract;
Proteasome Activation is Mediated via a Functional Switch of the Rpt6 C-terminal Tail Following Chaperone-dependent Assembly: V. Sokolova, et al.; Sci. Rep.
5, 14909 (2015),
Abstract;
Full Text
