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Proteasome 20S α5 subunit monoclonal antibody (MCP196)

 
BML-PW8125-0100 100 µl 478.00 USD
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Product Details

Alternative Name:Proteasome subunit α type-5, Macropain ζ chain
 
Clone:MCP196
 
Host:Mouse
 
Isotype:IgG2a
 
Immunogen:Dinitrophenylated human placenta derived proteasomes.
 
UniProt ID:P28066
 
Gene/Protein Identifier:PSMA5 (gene name)
 
Source:Purified from hybridoma tissue culture supernatant.
 
Species reactivity:Human, Mouse, Rat
Rabbit
 
Specificity:Recognizes the α5 subunit of the 20S proteasome.
 
Applications:IHC, WB
 
Purity Detail:Partially purified ascites.
 
Formulation:Liquid. In PBS containing 10mM sodium azide.
 
Handling:Avoid freeze/thaw cycles.
 
Shipping:Blue Ice
 
Long Term Storage:-20°C
 
Technical Info/Product Notes:Various systems for the nomenclature of the proteasome subunits have been established. This may be a source of confusion as the system on UniProt differs from "standard" nomenclature as described in the literature. The UniProt ID and Gene Name will help to clearly identify the proteins.
 
Regulatory Status:RUO - Research Use Only
 

Product Literature References

Proteasome stress sensitizes malignant pleural mesothelioma cells to bortezomib-induced apoptosis: F. Cerruti, et al.; Sci. Rep. 7, 17626 (2017), Abstract; Full Text
D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly: P. Barroso-Chinea, et al.; Neurobiol. Dis. 78, 77 (2015), Application(s): Western Blotting, Abstract;
TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions: Z. Lukic, et al.; Retrovirology 8, 93 (2011), Abstract; Full Text

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