Apstatin is a potent and selective inhibitor of aminopeptidase P (APP), Ki=2.6 µM for purified rat lung membrane-bound APP. It blocks the APP-mediated degradation of bradykinin. Limits myocardial infarct size alone or with ACE inhibitors.
Product Details
| Alternative Name: | N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-prolyl-L-prolyl-L-alaninamide |
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| Sequence: | N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-prolyl-L-prolyl-L-alaninamide |
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| Formula: | C23H33N5O5 |
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| MW: | 459.5 |
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| CAS: | 160470-73-5 |
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| Formulation: | Lyophilized. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | Solid. |
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| Solubility: | Soluble in water (>25 mg/ml) or DMSO (20 mg/ml). |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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