CTTHWGFTLC is a specific inhibitor of the gelatinases, MMP-2 and MMP-9, with an IC50 of 10-50 µM. Can be used in in vitro studies, zymography and in situ zymography, in tissue culture, and in vivo. Also available, negative control peptide STTHWGFTLS.
Product Details
| Alternative Name: | Gelatinase inhibitor |
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| Sequence: | H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH, cyclic peptide |
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| MW: | 1167.4 |
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| Source: | Synthetic. |
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| Formulation: | Lyophilized. |
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| Purity: | ≥95% (HPLC) |
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| Appearance: | White to off-white solid. |
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| Solubility: | Soluble in water at 1mg/ml. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Handling: | Protect from moisture. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Canstatin stimulates migration of rat cardiac fibroblasts via secretion of matrix metalloproteinase-2: M. Okada, et al.; Am. J. Physiol. Cell Physiol.
312, C199 (2017),
Abstract;
