AIP (autocamtide-2-related inhibitory peptide) is a highly specific and potent inhibitor of CaM kinase II. This peptide is derived from the CaM kinase II substrate autocamtide-2 (BML-P101) but alanine is substituted for threonine at the 9-position. AIP at 1 µM completely inhibited CaM kinase II but did not affect PKC, PKA, CaMKIV and other brain extract kinases. A cell-permeable, myristoylated version is available (BML-P212).
Product Details
| Alternative Name: | Autocamtide-2-related inhibitory peptide |
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| Sequence: | Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu |
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| MW: | 1498.0 |
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| Purity: | ≥97% |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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