A non-sulfonylurea inhibitor of K-ATP channels. Inhibits vascular K-ATP channels. Inhibits dopamine-modulated potassium channels.
Product Details
| Alternative Name: | N-(1-Adamantyl)-N'-cyclohexyl-4-morpholinecarboxamidine . HCl |
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| Formula: | C21H35N3O . HCl |
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| MW: | 382 |
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| CAS: | 57568-80-6 |
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| Purity: | ≥98% (TLC) |
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| Appearance: | White to off-white solid |
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| Solubility: | Soluble in water (5mg/ml). |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | Ambient |
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| Use/Stability: | Store, as supplied, at room temperature for up to 1 year. Store solutions at -20°C for up to 1 month. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Inhibition of vascular K(ATP) channels by U-37883A: a comparison with cardiac and skeletal muscle: G. C. Wellman, et al.; Br. J. Pharmacol.
128, 909 (1999),
Abstract;
Full Text
U-37883A potently inhibits dopamine-modulated K+ channels on rat striatal neurons: Y. J. Lin, et al.; Eur. J. Pharmacol.
352, 335 (1998),
Abstract;
