A guggul tree steroid well known for its lipid lowering properties. Acts as a selective antagonist at farnesoid X receptors (FXRs). Inhibits FXR transactivation (IC50=10µM).
Product Details
| Formula: | C21H28O2 |
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| MW: | 312.5 |
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| CAS: | 39025-23-5 |
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| Purity: | ≥98% |
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| Appearance: | White solid. |
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| Solubility: | Soluble in DMSO. |
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| Shipping: | Ambient Temperature |
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| Long Term Storage: | -20°C |
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| Use/Stability: | Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months. |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
A natural product that lowers cholesterol as an antagonist ligand for FXR: N. L. Urizar, et al.; Science
296, 1703 (2002),
Abstract;
