Note: Users should note that the antiserum is specific to the X-R-F-NH2 terminus and, accordingly, bioactive peptides with similar C-terminal sequences (e.g. mammalian g1-MSH9 and other N-terminally extended forms) may give strong positive immunostaining on certain tissues. The use of proteolytic enzymes (e.g. trypsin) to improve immunostaining should also be avoided as this may result in the appearance of 'false positive' staining due to the enzymatic induction of reactive -R-F-NH2 from nonreactive -R-F-G-K/R-K/R- pro-hormone sequences.
Product Details
| Alternative Name: | Phe-Met-Arg-Phe-amide |
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| Host: | Rabbit |
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| Immunogen: | Synthetic FMRF-amide (Phe-Met-Arg-Phe-amide). |
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| UniProt ID: | O15130 |
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| Source: | Whole rabbit serum. |
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| Species reactivity: | Species independent
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| Specificity: | Recognizes FMRF in multiple species including human. |
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| Applications: | IHC
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| Formulation: | Liquid. Neat serum containing 0.1% sodium azide. |
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| Handling: | Avoid freeze/thaw cycles. |
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| Shipping: | Blue Ice |
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| Long Term Storage: | -20°C |
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| Regulatory Status: | RUO - Research Use Only |
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Product Literature References
Balanced release of neuropeptide FF and gonadotropin-releasing hormone 3 modulates male sexual behavior: C. Umatani, et al.; J. Neurophysiol.
163, 261 (2022),
Abstract;
High cell diversity and complex peptidergic signaling underlie placozoan behavior: F. Varoqueaux, et al.; Curr. Biol.
28, 3495 (2018),
Application(s): IF using Trichoplax adhaerens,
Abstract;
Brain anatomy in Diplura (Hexapoda): A. Böhm, et al.; Front. Zool.
9, 26 (2012),
Application(s): IF using diplura head tissue section,
Abstract;
Full Text
Organization of the nervous system in Opisthorchis viverrini investigated by histochemical and immunohistochemical study: R. Leksomboon, et al.; Parasitol. Int.
61, 107 (2012),
Application(s): IF using trematodes,
Abstract;
Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons: T.H. Saito, et al.; J. Neurophysiol.
104, 3518 (2010),
Application(s): IHC using fish brain tissue section,
Abstract;
