VEGF receptor tyrosine kinase inhibitor. Inhibits KDR (IC50=100nM) and Flt (IC50=2µM) tyrosine kinases.
Product Details
Formula: | C16H13ClFN3O2 |
|
MW: | 333.7 |
|
CAS: | 690206-97-4 |
|
Purity: | ≥98% (TLC) |
|
Appearance: | Off-white solid. |
|
Solubility: | Soluble in DMSO (3 mg/ml) or ethanol (1 mg/ml). |
|
Shipping: | Ambient Temperature |
|
Long Term Storage: | Ambient |
|
Use/Stability: | Store, as supplied, at room temperature for up to 1 year. |
|
Regulatory Status: | RUO - Research Use Only |
|
Please mouse over
Product Literature References
Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors: L.F. Hennequin, et al.; J. Med. Chem.
42, 5369 (1999),
Abstract;